At the tenth annual conference held in Frankfurt-Main, Germany, the experts of medicinal glass bottles proposed the main chemical composition, chemical stability and physical performance technical indicators of 3.3 -borosilicate glass and neutral glass. Among them, 3.3 -borosilicate glass and China's special hard material, GG17 material chemical composition and physical and chemical properties are basically the same, the main difference lies in the control range of the coefficient of thermal expansion of the line is different, China's two kinds of glass has not strictly specified the range of thermal expansion coefficient control. The difference between the performance of international neutral glass bottles and China's " neutral " glass is obvious. In the future, it is necessary to actively develop international neutral glass production, and the " neutral " glass that gradually restricts the use of our original concept is becoming a consensus among people in the industry. .
In China, low borosilicate glass is a so-called " neutral " glass that has been used for many years. Compared with international neutral glass, the difference in chemical composition between the two is very large. China's " neutral " glass has a low boron content, so the coefficient of thermal expansion of the wire is large, and the water resistance of the particles cannot maintain the HGB1 level. This is because China's " neutral " glass material is more general, so it reflects the water resistance on the internal surface is also poor - the international neutral glass surface water resistance can guarantee to achieve ISO4802-HC1 requirements, and China's " neutral " glass is very Difficult to reach. In the international standard ISO12775-1997 “Normally Large-scale Production of Glass by Component Classification and Test Methodâ€, packaging glass has been clearly divided into three types: international neutral glass, borosilicate glass, and soda-lime glass.
In the international standard, soda-lime glass is not indicated as medicinal, and international neutral glass is the glass of choice for medicinal glass bottles recognized in the world, and it is also referred to as grade A amber glass in the domestic pharmaceutical industry. Bottle, 5.0 glass or grade A material, where 5.0 refers to its expansion coefficient is not greater than 5.0 × 10-6. Because this glass's water resistance, acid resistance, alkali resistance is a grade, it can be said to have excellent Chemical stability and thermal stability, as medicinal glass bottles, have unparalleled advantages for ensuring the quality of medicines.
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