Large area burns usually transplant skin from other parts of the body to the burn site. Although this is a common method, burn wounds do not always heal completely. The team showed that leukocyte soluble factors improve tissue healing after skin grafting. This research has been published in the top journal Scientific Reports.
Burn patients often have larger wounds, and the damaged skin cannot heal, so it must be removed. Usually, skin grafts are generally transplanted from the skin of the thigh root or the skin of the patient's back is transplanted to the injured site. These wounds are more likely to heal in younger patients, but this healing process takes a considerable amount of time (such as diabetes) in elderly patients and those with certain diseases. Sometimes if a complication occurs, you will need to re-do an operation and even leave ugly scars.
The team led by Stefan Hacker used animal models to demonstrate a method in which soluble factors in white blood cells can cause significant improvements in tissue repair. In this method, leukocytes release certain proteins by gamma ray irradiation, stimulating angiogenesis and tissue regeneration. Secretion factor treatment drugs are used for wound treatment. Studies have shown that an increase in the number of blood vessels is faster and better promotes skin growth than in the control group.
The study is an excellent example of a translational study that can benefit patients quickly. Stefan Hacker said: "The clinical application of the human body should not be limited to burns, but it can also be applied to other types of wounds. For example, after microsurgical tissue transplantation, it can treat diabetic skin ulcers or poor wound healing." (Bio Valley Bioon. Com)
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